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Common symptoms of rheumatoid arthritis include: Joint pain that is symmetrical (affecting both sides of the body) Morning stiffness that lasts longer than 30 minutes Swollen joints , especially in the hands, wrists, and knees Fatigue and low energy that feels constant or unrelenting Warm or tender joints , particularly after periods of rest Reduced range of motion or difficulty with fine motor tasks Muscle aches that are not related to exercise or injury Low-grade fevers or flu-like symptoms that come and go Weight loss that is unintentional and accompanied by fatigue Depression or mood changes , often related to chronic pain During menopause , the loss of estrogens protective effects can make RA symptoms worse

kits comprising an antibody construct of the invention or produced according to the process of the invention, a pharmaceutical composition of the invention, a polynucleotide of the invention, a vector of the invention and/or a host cell of the invention

They are generally odorless, colorless, and tasteless if pure, but they may be flavored according to origin